Research in our group focuses on using new spectroscopic techniques to probe chemistry at the ultimate limits of space and time. We investigate fundamental and applied issues in membrane protein biophysics, alternative energy sources, and nanotechnology, determining how local environments affect chemistry. Currently, we are working on developing a label-free, super-resolution imaging technique to monitor cells on the nanometer length scale, determining the role of vibrations in driving electron transfer reactions, and using plasmonic nanomaterials to monitor and catalyze chemical reactions. Our research is highly interdisciplinary, investigating current problems at the interface of chemistry, biology, and materials science.

Recent News and Publications
Plasmon-Mediated Intramolecular Methyl Migration with Nanoscale Spatial Control
Brooks, J. L., Warkentin, C. L., Chulhai, D. V., Goodpaster, J. D., Frontiera, R. R. ACS Nano, 2020

Quinine copolymer reporters promote efficient intracellular DNA delivery and illuminate a protein-induced unpackaging mechanism
Van Bruggen, C., Punihaole, D., Keith, A. R., Schmitz, A. J., Tolar, J., Frontiera, R. R., Reineke, T. M., Proceedings of the National Academy USA, 2020

Advances in Singlet Fission Chromophore Design Enabled by Vibrational Spectroscopies
Bera, K.*, Kwang, S. Y.*, Frontiera, R. R. The Journal of Physical Chemistry C, 2020. Cover
