Research in our group focuses on using new spectroscopic techniques to probe chemistry at the ultimate limits of space and time. We investigate fundamental and applied issues in membrane protein biophysics, alternative energy sources, and nanotechnology, determining how local environments affect chemistry. Currently, we are working on developing a label-free, super-resolution imaging technique to monitor cells on the nanometer length scale, determining the role of vibrations in driving electron transfer reactions, and using plasmonic nanomaterials to monitor and catalyze chemical reactions. Our research is highly interdisciplinary, investigating current problems at the interface of chemistry, biology, and materials science.


Recent News and Publications

Decoding Chemical and Physical Processes Driving Plasmonic Photocatalysis Using Surface-Enhanced Raman Spectroscopies

Warkentin, C. L.*, Yu, Z.*, Sarkar, A., Frontiera, R. R. Accounts of Chemical Research2021

acr toc

Plasmon-Mediated Intramolecular Methyl Migration with Nanoscale Spatial Control

Brooks, J. L., Warkentin, C. L., Chulhai, D. V., Goodpaster, J. D., Frontiera, R. R. ACS Nano2020


Quinine copolymer reporters promote efficient intracellular DNA delivery and illuminate a protein-induced unpackaging mechanism

Van Bruggen, C., Punihaole, D., Keith, A. R., Schmitz, A. J., Tolar, J., Frontiera, R. R., Reineke, T. M., Proceedings of the National Academy USA2020